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Allopurinol

  • $0.67
  • Availability: In Stock
  • Active Ingredient allopurinol
Allopurinol is an arthrifuge which inhibits xanthine oxidase and prevents formation of uric acid, from xanthine and hypoxanthine.
Analogs of Allopurinol: Zyloprim  
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Other names of Allopurinol: a   b   c   d   e   f   g   h   i   j   k   l   m   n   o   p   q   r   s   t   u   v   w   x   y   z  
Atisuril   Apurol   Apurin   Apo-allopurinol   Aluline   Alositol   Aloral   Alopurinol   Aloprim   Allurit   Allural   Allozym   Allopurinolum   Allopurinolo   Allopurin   Allopur   Alloprim   Allopim   Allohexal   Allobeta   Allobenz   Allo-puren   Allo   Alfadiman   Aideito   Adenock   Alopurinol   Allopurinolo   A.P.N.   Acpurin   Adco-Allopurinol   AL   Aleze   Alfadiman   Allo Comp   Allo X   Alloben   Allobeta   Allocor   Allo-CT   Allomaron   Allonol   Allopac   Allopin   Alloprim   Allopsel   Allopur   Allopurine   Allopurinol - 1 A Pharma   Allopurinol AbZ   Allopurinol Accord   Allopurinol Actavis   Allopurinol AL   Allopurinol Alpharma   Allopurinol Apotex   Allopurinol Arena   Allopurinol Arrow   Allopurinol Aurobindo   Allopurinol Biogaran   Allopurinol BTT   Allopurinol CF   Allopurinol Chemiphar   Allopurinol Chen Ta   Allopurinol Cherubino   Allopurinol Community Pharm   Allopurinol CP   Allopurinol Craveri   Allopurinol Crescent   Allopurinol DAK   Allopurinol DHA   Allopurinol Dosa   Allopurinol dura   Allopurinol EG   Allopurinol Fabra   Allopurinol G.L.   Allopurinol Gador   Allopurinol Genericon retard   Allopurinol Helvepharm   Allopurinol Hexal   Allopurinol Hexpharm   Allopurinol Hisun   Allopurinol Hovid   Allopurinol Inca   Allopurinol Isomed   Allopurinol Kyorin Rimedio   Allopurinol Kyowa Yakuhin   Allopurinol Landson   Allopurinol Meider   Allopurinol Mylan   Allopurinol Nichi-iko   Allopurinol Nordic Drugs   Allopurinol Nycomed   Allopurinol Panbiotic   Allopurinol PCH   Allopurinol Pharmacare   Allopurinol Phoenix   Allopurinol PHR Lab   Allopurinol Quality Pharm   Allopurinol Ranbaxy   Allopurinol ratiopharm   Allopurinol Retard   Allopurinol Sandoz   Allopurinol Sawai   Allopurinol Showa Yakuhin Kako   Allopurinol SIC   Allopurinol Stada   Allopurinol Standard   Allopurinol Takata   Allopurinol Teva   Allopurinol Towa   Allopurinol U.C. Pharma   Allopurinol Wockhardt   Allopurinol Yung Shin   Allopurinol ZE   Allopurinol Zentiva   Allopurinol Zydus   Allopurinol-Egis   Allopurinol-Hisun   Allopurinol-Mepha   Allopurinolo Molteni   Allopurinolo Sandoz   Allopurinolo Teva Italia   Allopurinol-ratiopharm   Allopurinol-ratiopharm comp.   Allopurinol-Teva   Alloric   Alloril   Allorin   Allostad   Allozym   Allupol   Allurase   Alluric   Allurit   Alodagra   Alodan   Alofar   Aloprinol   Alopron   Alopurinol Andromaco   Alopurinol Belupo   Alopurinol Chemopharma   Alopurinol Ciclum   Alopurinol Cinfa   Alopurinol Ecuaquímica   Alopurinol Hemofarm   Alopurinol Kern Pharma   Alopurinol Merck   Alopurinol Mintlab   Alopurinol Mundogen   Alopurinol Nifa   Alopurinol Normon   Alopurinol Pensa   Alopurinol PharmaS   Alopurinol Ratiopharm   Alopurinol Sandoz   Alopurinol Teva   Aloric   Alositol   Alpurase   Alputon   Aluric   Alurin   Alurol   Aluron   Anoprolin   Anpurin   Ao Mai Bi Li   Apllinol   Apo Allopurinol   Apo-allopurinol   Artrex   Arythmet   Atisuril   Aurinol   Acepurin   Allopurinol Sodium Bedford   Aloprim  
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300 mg
Product name Per Pill Per Pack  
30 pills $1.11 $33.36
60 pills $0.87 $66.71 $52.16
90 pills $0.79 $100.07 $70.96
120 pills $0.75 $133.43 $89.76
180 pills $0.71 $200.14 $127.37
270 pills $0.68 $300.21 $183.76
360 pills $0.67 $400.28 $240.16

Product Description

Common use
Allopurinol is an arthrifuge which inhibits xanthine oxidase and prevents formation of uric acid, from xanthine and hypoxanthine. Reduces the concentration of uric acid and its salts in body fluids, promotes the dissolution of existing urate deposits and prevents their formation in tissues and kidneys. The medication is used to treat diseases accompanied by hyperuricemia: gout (primary and secondary), nephrolithiasis (forming of kidney stones from urates); hyperuricemia (abnormally high level of uric acid in blood, both primary and secondary), which results in diseases involving enhanced dissolution of nucleoproteins and elevated levels of uric acid in the blood, including at various forms of leukemias, and also for treatment of some other conditions.

Dosage and direction

The dose of 100-800 mg a day may be prescribed depending on the condition. Initial dose of 100 mg can be increased gradually. Patients with acute gout and tophi (uric acid crystals in the tissues mostly around joints) should be treated with 300-400 mg of Allopuionol daily. Doses over 300 mg should be divided in two or more intakes. Take medication with food to avoid irritation of the stomach. Do not take large doses of vitamin C. Drink plenty of water to avoid formation of kidney stones. Limit consummation of alcoholic beverages and purine-rich foods such as sweetbreads, sardines, anchovies, kidneys, liver, and lentils.

Precautions

Allopurinol should be taken over a period of several months so your symptoms start to reduce. Regular intake is important even if no immediate effect is noticed. You may experience acute attacks of gout more often at the beginning of treatment with Allopurinol even after normal uric acid levels are reached. The attacks will become shorter and less acute as the therapy continues. At any sign of allergic reaction stop taking the medication and consult your doctor as development of serious skin disease, irreversible damage to the liver, or generalized inflammation of a blood or lymph vessel is possible in some individuals. Inform your doctor if you have diabetes or kidney dysfunction before taking Allopurinol as correction of your dose is needed.

Contraindications

Allopurinol cannot be used in patients with hypersensitivity to the medication, in individuals with a hepatic or renal disorders, primary hemochromatosis, asymptomatic hyperuricemia, acute gout, pregnancy, lactation. The medication cannot be prescribed to children under 14 years of age unless the patients are treated for leukemia, malignant tumors and enzymatic disorders. C care. Renal failure, heart failure, diabetes mellitus, hypertension.

Possible side effect

The most common adverse reactions are diarrhea, nausea, allergy (rash, itching), and drowsiness. Stop taking the medication at first signs of rash, painful or bloody urination, eye irritation, or facial swelling, because these can be signs of a severe allergic reaction requiring immediate treatment. In rare cases Allopurinol can cause damage to nerve, kidney, and bone marrow as well as be a reason to a serious and even fatal allergic liver toxicity. In patients with liver toxicity appetite loss and itching may witness about it. The risk increases in patients with kidney impairment.

Drug interaction

The dose of oral mercaptopurine (Purinethol) and azathioprine (Imuran) should be reduced as Allopurinol increases their blood levels. Risk of skin rash increases in patients taking Allopurinol with penicillins.

Missed dose

Take the missed dose as soon as you remember unless it is almost time of your next dose. If it is almost time of your next dose just skip it and return to your regular scheme. Do not exceed the recommended dose.

Overdose

In case of suspected overdose seek for immediate medical attention. No specific information is available about Allopurinol overdose.

Storage

Store at room temperature, below 25 C (77 F) and out of reach and children and pets.

Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information on the site cannot be used for self-treatment and self-diagnosis.All specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

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Safety of the medication and the risk of adverse reactions are important questions that bother the vast majority of clients. Ordering the treatments online, you need to be aware of all the responsibilities. Contact your medical specialist or seek emergency medical assistance in case you have noticed any of the following problems:

Rare

  • Abdominal or stomach pain
  • agitation
  • ammonia-like breath odor
  • anxiety
  • bleeding gums
  • blistering, peeling, or loosening of the skin
  • blood in the urine or stools
  • bloody nose
  • bloody or black, tarry stools
  • blue or pale skin
  • bruising
  • changes in skin color
  • chest pain or discomfort
  • chest pain, possibly moving to the left arm, neck, or shoulder
  • chills
  • clay-colored stools
  • cloudy urine
  • coma
  • confusion
  • constipation
  • cough or hoarseness
  • coughing up blood
  • cracks in the skin
  • dark urine
  • decreased urine output
  • depression
  • diarrhea
  • difficulty with breathing
  • dizziness
  • drowsiness
  • dry mouth
  • feeling faint, dizzy, or lightheaded
  • feeling of warmth or heat
  • fever
  • fever with or without chills
  • flushing or redness of the skin, especially on the face and neck
  • general feeling of discomfort or illness
  • general feeling of tiredness or weakness
  • headache
  • hostility
  • incoherent speech
  • increased urination
  • irritability
  • itching
  • joint or muscle pain
  • large, flat, blue or purplish patches in the skin
  • lethargy
  • light-colored stools
  • loss of appetite
  • loss of heat from the body
  • lower back or side pain
  • metallic taste
  • muscle twitching
  • muscle weakness
  • nausea or vomiting
  • pain, tenderness, or swelling of the foot or leg
  • painful or difficult urination
  • pinpoint red or purple spots on the skin
  • rapid weight gain
  • rash
  • red, irritated eyes
  • red, swollen skin
  • redness, soreness, or itching skin
  • right upper abdominal or stomach pain and fullness
  • scaly skin
  • seizures
  • severe stomach pain
  • shortness of breath
  • slow or irregular heartbeat
  • sore throat
  • sores, ulcers, or white spots on the lips or in the mouth
  • sores, welting, or blisters
  • stupor
  • sweating
  • swelling of the face, ankles, hands, or lower legs
  • swollen or painful glands
  • swollen, painful, or tender lymph glands in the neck, armpit, or groin
  • thirst
  • tightness in the chest
  • unpleasant breath odor
  • unusual bleeding or bruising
  • unusual weight gain or loss
  • vomiting of blood or material that looks like coffee grounds
  • wheezing
  • yellow eyes or skin
  • Bad, unusual, or unpleasant (after) taste
  • blindness
  • blue-yellow color blindness
  • blurred vision
  • body aches or pain
  • burning feeling in the chest or stomach
  • burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
  • burning, dry, or itching eyes
  • burning, numbness, tingling, or painful sensations
  • change in taste
  • change in vision
  • congestion
  • continuing ringing or buzzing or other unexplained noise in the ears
  • decreased interest in sexual intercourse
  • decreased vision
  • difficulty with moving
  • discharge or excessive tearing
  • feeling of constant movement of self or surroundings
  • hair loss or thinning of the hair
  • hearing loss
  • hives or welts
  • impaired vision
  • inability to have or keep an erection
  • indigestion
  • lack or loss of strength
  • loss in sexual ability, desire, drive, or performance
  • loss of appetite
  • loss of memory
  • multiple swollen and inflamed skin lesions
  • muscle aching or cramping
  • muscle pain or stiffness
  • muscular pain, tenderness, wasting, or weakness
  • noisy breathing
  • problems with memory
  • redness, pain, or swelling of the eye, eyelid, or inner lining of the eyelid
  • runny nose
  • sensation of spinning
  • sensitivity to light
  • sleepiness or unusual drowsiness
  • sleeplessness
  • sneezing
  • stomach upset
  • stuffy nose
  • sweating
  • swelling of the breasts or breast soreness in both females and males
  • swelling of the salivary glands
  • swelling or inflammation of the mouth
  • swollen joints
  • tearing
  • tender, swollen glands in the neck
  • tenderness in the stomach area
  • throbbing pain
  • tightness in the chest
  • trouble getting pregnant
  • trouble with sleeping
  • trouble with swallowing
  • unable to sleep
  • unsteadiness or awkwardness
  • voice changes
  • weakness in the arms, hands, legs, or feet
  • weight loss

More Common

  • Ankle, knee, or great toe joint pain
  • joint stiffness or swelling
  • rash
  • rash with flat lesions or small raised lesions on the skin
Type Small Molecule
Accession Number DB00437  (APRD00435, DB03027)
Groups Approved
Synonyms
  • 1,5-Dihydro-4H-pyrazolo(3,4-d)pyrimidin-4-one
  • 1,5-Dihydro-4H-pyrazolo(3,4-d)pyrimidine-4-one
  • 1H-Pyrazolo(3,4-d)pyrimidin-4-ol
  • 4-HPP
  • 4-Hydroxy-1H-pyrazolo(3,4-d)pyrimidine
  • 4-Hydroxy-3,4-pyrazolopyrimidine
  • 4-Hydroxypyrazolo(3,4-d)pyrimidine
  • 4-Hydroxypyrazolopyrimidine
  • 4-Hydroxypyrazolyl(3,4-d)pyrimidine
  • 4'-Hydroxypyrazolol(3,4-d)pyrimidine
  • 4H-Pyrazolo(3,4-d)pyrimidin-4-one
  • Allopurinolum
  • Alopurinol
UNII 63CZ7GJN5I
CAS number 315-30-0
Weight Average: 136.1115
Monoisotopic: 136.03851077
Chemical Formula C5H4N4O
InChI
InChI=1S/C5H4N4O/c10-5-3-1-8-9-4(3)6-2-7-5/h1-2H,(H2,6,7,8,9,10)
IUPAC Name
1H,2H,4H-pyrazolo[3,4-d]pyrimidin-4-one
Protein binding

Allopurinol and oxypurinol are not bound to plasma proteins

Toxicity

LD50=214 mg/kg (in mice)

Half life

1-3 hours

Our company is constantly expanding and developing for you. Striving to provide you with the best services, we offer a worldwide shipping to the most diverse countries and cities, as well as the following cities in Philippines:

  • Manila
  • Cebu
  • Davao
  • Cagayan de Oro
  • Angeles
  • Iloilo City-Guimaras
  • Naga
  • Bacolod
  • Baguio-LISTT
  • Batangas City

The delivery time will depend mainly on the destination, but in general, it ranges from 3 to 14 days.